When: Sunday, December 12th, 2021 at 4:25PM ET.

Where: Paul Brown Stadium, Cincinnati, OH.

How: CBS.

Spread: 49ers -2.

Total: 49.

Odds courtesy of FanDuel Sportsbook

49ers Spotlight

The San Francisco 49ers are 3-2 ATS as a road favorite this season but did take the L last Sunday in Seattle failing to cover 2.5 point spread in 30-23 loss.  The key difference for San Fran here is they will for the first time be road favorites against an opponent with a winning record. 

Bengals Spotlight

The Cincinnati Bengals have been schizophrenic the past 4 games looking like Super Bowl contenders one week and appearing to be a low functioning coma patient the next... last week we hit the Chargers mid-tier play as they totally nut kicked the Bengals.

Final Say

This game will be physical upfront for sure and I think San Fran will present a few problems running the ball and a big pass rush... however, Bengals are perfectly positioned to bounce back in the role of small home dog and with a capable offense they send their guests home humbled.  

CINCINNATI 27 San Francisco 23.

Pick: Cincinnati Bengals +1.5